
Image: The Hindu
Crescel's new biobotanical Skin Renewal Cream shows promising results in treating rosacea, surpassing traditional therapies in a recent clinical trial.
GlipzoOn March 20, 2026, Crescel LLC, a pioneering company in the field of skin health, unveiled compelling results from a double-blind, randomized controlled clinical trial. This significant study focused on their innovative biobotanical Skin Renewal Cream, which was compared against the widely used treatment of topical metronidazole (Metrocream®) in conjunction with CeraVe® moisturizer. The trial specifically targeted individuals suffering from rosacea, a persistent and often distressing skin condition.
Conducted under the guidance of a highly regarded dermatologist, the study enrolled 60 adult participants diagnosed with varying degrees of rosacea, ranging from mild to severe. Over a 12-week treatment period, researchers meticulously evaluated the effectiveness of Crescel's formulation against the standard treatment regimen. The complete findings are set to be submitted for publication in a reputable peer-reviewed medical journal later this year.
The participants were randomly assigned to receive either the Crescel Skin Renewal Cream or a combination of metronidazole 0.75% and a moisturizer, applied twice daily. Dermatologist assessments were performed at multiple intervals: baseline, Week 4, Week 8, and Week 12. The results were particularly striking:
The Crescel Skin Renewal Cream is formulated with a unique blend of naturally sourced ingredients, enhanced by a proprietary microemulsion delivery system that aims to bolster skin health effectively. This innovative approach has earned the National Rosacea Society Seal of Acceptance and the National Psoriasis Foundation Seal of Recognition, highlighting its credibility in managing skin conditions.
Peter J. Passalacqua, Jr., Co-Founder, Chairman, and CEO of Crescel, remarked, “These findings support the potential for a new approach in managing rosacea. In this controlled clinical trial, Crescel demonstrated greater improvement across key measures compared to a commonly used standard regimen, with a favorable tolerability profile.”
The trial has garnered positive attention not only for its results but also for the endorsement of leading medical professionals. Dr. Roberta Shapiro, a senior medical advisor at Crescel and a specialist in Regenerative Medicine and Rehabilitation at Columbia University Medical Center, stated, “Crescel’s healing capabilities are exceptional. I have never seen anything like this in my 30 years of practicing rehabilitation medicine.” This endorsement adds weight to the claims made by Crescel about the efficacy of their product.
Beyond rosacea, the Crescel Skin Renewal Cream has been evaluated for its effectiveness in treating other skin-related ailments, including: - Psoriasis - Eczema - Acne - Diabetic ulcers
This versatility positions Crescel not just as a niche player in the dermatology market, but as a potential leader in the broader field of skincare solutions.
The findings from Crescel's trial are particularly important as they introduce a promising alternative for patients grappling with rosacea—a condition that can significantly impact the quality of life. With over 16 million Americans affected by rosacea, the introduction of a more effective and better-tolerated treatment could change the landscape of dermatological care.
As Crescel prepares to submit its findings for peer review, industry experts and consumers alike are keenly watching the developments. The positive trial results could lead to: - Increased market demand for the Skin Renewal Cream, especially among rosacea sufferers seeking new treatment options. - Potential collaborations with dermatologists and clinics to further validate and promote the product. - Expansions into retail markets, making the cream accessible to a broader audience.
In conclusion, Crescel's innovative approach towards treating rosacea not only adds a noteworthy option to the existing treatment landscape but also highlights the ongoing evolution of skincare solutions. As more data becomes available, the impacts on patient care and overall skin health could be transformative.
For those interested in exploring this novel solution, Crescel Skin Renewal Cream is currently available for purchase online at www.crescel.com.

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